Research Results
Beta Version
Use the search bar below to find studies, or apply one or more filters to narrow your results. See our list of keywords to guide your search.
Search by keyword
Select
Select
- All Risk Factors
- Air Pollution
- Alcohol
- Antimicrobials
- Artificial sweeteners
- Bisphenols
- Body Weight
- Breast Density
- Chemical Mixtures
- Chemicals in products
- Cleaning Products
- Diet
- Exercise
- Family History
- Furniture & Electronics
- Genetics
- Gut Health
- Hair Dye
- Hormones
- Inflammation
- Job
- Light at night
- Metals
- Neighborhood
- Night Shift Work
- Noise
- Non-stick Pans & Waterproof Gear
- Oral Contraceptives
- PAHs
- Parabens
- PCBs
- Personal Care Products
- Pesticides
- PFAS
- Pharmaceuticals
- Place-based
- Plastic
- Pregnancy & Breastfeeding
- Processed Food
- Puberty Age
- Race/Ethnicity
- Radiation
- Red meat
- Scented Products & Soft Plastic
- Sleeping Patterns
- Soda
- Stress
- Sugar
- Sunscreen
- Tobacco
- Vitamin D
Select
Select
Select
Select
Select the Chemical Agents
- All Chemical Agents
- 1,1,2,2-TCA
- 1,3-Butadiene
- Acrolein
- Aldrin
- Alkylphenols
- Antimicrobials
- Antimicrobials: QACs, Triclosan, Triclocarban
- Aromatic Amines
- Arsenic
- Artificial Sweeteners
- Atrazine
- Benzene
- Bisphenols
- Cadmium
- Chlordane
- Chlorpyrifos
- DDT
- Dibutyl Phthalate
- Dichlorvos
- Dieldrin
- Dioxins
- ell/
- Ethanol (alcohol)
- Ethyl Benzene
- Ethylene Oxide
- Flame Retardants
- Food
- Formaldehyde
- Glyphosate
- Heptachlor
- Hormones
- Insulin
- Lead
- Light at Night
- Mercury
- Metals
- Methoxyclor
- Naphthalene
- Night Shift Work
- Nitrogen Dioxide
- Noise
- Oral Contraceptives
- Organochlorine Pesticides
- Organophosphate Pesticides
- Ozone
- PAHs
- Parabens
- Particulate Matter
- PCBs
- Pesticides
- PFAS
- Phenols
- Phthalates
- Processed Food
- PVC
- Radiation: Ionizing
- Radiation: Non-Ionizing
- Soda
- Stress
- Sugar
- Tobacco
- Toluene
- Trichloroethylene
- Triclosan
- Ultraviolet Radiation
- UV Filters
- Vinyl Chloride
Select the Study Tags
Sort By
- Relevance
- Title (A to Z)
- Title (Z to A)
- Publication Year (Ascending)
- Publication Year (Descending)
- Authors (A to Z)
- Authors (Z to A)
2022
Ecotoxicology
An experimental study using wild-type and thyroid hormone receptor alpha knockout (thrαa⁻/⁻) zebrafish embryos/larvae found that avobenzone and octinoxate—organic UV filters commonly used in sunscreens and widely detected in water—disrupt the thyroid endocrine system, with significantly lower survival rates in thrαa⁻/⁻ fish exposed to ≥3 μM of either compound, indicating the thyroid hormone receptor plays a crucial role in their toxicity. Avobenzone exposure increased the T3:T4 ratio with upregulation of the deio2 gene, while both chemicals decreased T4 levels and triggered compensatory upregulation of hypothalamus and pituitary genes (trh, tshβ, tshr), indicating feedback mechanisms attempting to maintain hormonal homeostasis. These findings demonstrate that two widely used sunscreen ingredients act as thyroid endocrine disruptors by affecting thyroid hormone receptors and disrupting the hypothalamus-pituitary-thyroid (HPT) axis, raising concerns about aquatic environmental contamination from these chemicals and potential impacts on thyroid function in exposed organisms, including implications for human exposure through water and dermal application.
2020
Medicine
A meta-analysis of 6 studies found that exposure to solar ultraviolet (UV) radiation was associated with a 30% reduced breast cancer risk overall, with a dose-response analysis showing a linear protective relationship in women over 40 (14% risk reduction per unit increase in UV exposure). Notably, not tanning and covering the limbs were associated with increased breast cancer risk, while sunscreen use showed no association with risk, suggesting that actual UV skin exposure—rather than ambient UV levels alone—may be the key protective factor. This is the first dose-response meta-analysis demonstrating that higher UV exposure correlates with lower breast cancer risk in a linear fashion among middle-aged and older women, likely through Vitamin D production, though the findings highlight the complex balance between skin cancer risks from excessive UV exposure versus potential breast cancer protection from adequate sun exposure, and the need for further research on how factors like estrogen receptor status, Occupation, and ethnicity modify this relationship.
2012
Environ Health Perspect
This study analyzed 213 everyday products, including cosmetics, cleaners, and personal care items, for endocrine-disrupting chemicals (EDCs) and asthma-related compounds. Testing revealed 55 chemicals, with fragranced products and sunscreens containing the highest levels. Vinyl products were also found to contain significant amounts of bis(2-ethylhexyl) phthalate (DEHP), a known EDC. Many harmful chemicals were not listed on product labels, limiting consumer ability to avoid them. These results highlight the presence of potentially harmful chemicals in commonly used products, raising concerns about their widespread use in household and personal care items.